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Description of Antiviral drugs

Antiviral medicinal drugs are a class of treatment used for treating viral infections

indications, Dosage, aspect effects, Contraindications, Interactions Precaution of Nucleoside Reverse Transcriptase Inhibitors

Nucleoside Reverse Transcriptase Inhibitors (NRTIs) include:

• Zidovudine (AZT)
• Lamivudine (3TC)
• Abacavir (ABC)
• Emtricitabine (FTC)
• Stavudine (d4T)
• Tenofovir (TDF)
o Tenofovir is categorized as Nucleotide Reverse Transcriptase Inhibitor

signals
-Nucleoside Reverse Transcriptase Inhibitors (NRTIs) are antiretroviral medicinal drugs that are indicated for remedy of HIV/AIDS in mixture with different antiretrovirals

Dose and Dosage

Zidovudine (AZT) 300 mg PLUS Lamivudine (3TC) a hundred and fifty mg twice every day

Tenofovir (TDF) 300mg PLUS Lamivudine (3TC) one hundred fifty mg twice daily

facet results
• Gastrointestinal disturbances (nausea, vomiting, belly agony, diarrhoea)
• Lactic acidosis
• Lipodystrophy
• Anaemia through Zidovudine
• Hypersensitivity by Abacavir
• Peripheral neuropathy by means of Stavudine
• Nephrotoxicity via Tenofovir

Contraindications
• Zidovudine is contraindicated to sufferers with Anaemia
• patients who're hypersensitive to the NRTIs
• Tenofovir is contraindicated to patients with renal failure

Interactions
expanded danger of haematological toxicity when Zidovudine given with NSAIDs

Precautions
• monitor liver perform when making use of NRTIs
• reveal renal operate when utilising Tenofovir
• screen pink blood mobilephone rely when utilising Zidovudine